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Downregulation of Thyroid Hormone Receptor Subtype mRNA Levels by Retinoic Acid in Cultured Cardiomyocytes

โœ Scribed by V. Drvota


Book ID
115581493
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
70 KB
Volume
242
Category
Article
ISSN
0006-291X

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Butyrate produced a biphasic modulation of the thyroid hormone receptor in neuroblastoma N2A cells increasing receptor number by 20-35 % at concentrations 0.25-0.75 mM and decreasing receptor levels by 3045% at 2 4 mM. The half-life of the receptor, as assessed by its disappearance after incubation