## Abstract RASSF2 can bind directly to KβRas and function as a negative effector of __Ras__ protein. RASSF2A is the only isoform of __RASSF____2__ that contains CpG islands in its promoter and it has been reported to be inactivated by its promoter methylation in several human cancers. In the prese
Downregulation of RECK by promoter methylation correlates with lymph node metastasis in non-small cell lung cancer
β Scribed by Huang-Chou Chang; Chun-Yu Cho; Wen-Chun Hung
- Book ID
- 108583792
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 168 KB
- Volume
- 98
- Category
- Article
- ISSN
- 1347-9032
No coin nor oath required. For personal study only.
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ADAM (a disintegrin and metalloproteinases) are a recently discovered gene family of proteins with sequence similarity to the reprolysin family of snake venom metalloproteinases, and about one-third of the family members have the catalytic site consensus sequence in their metalloproteinase domains.
## Abstract Tumor cell migration into the lymph nodes is an important aspect of cancer, yet little is known about the processes involved. CCR7 has been shown to play an important role in tumor cell migration and lymph node metastasis. The aim of our study was to evaluate the expression of __CCR7__