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Downregulation of osteopontin and bone sialoprotein II is related to reduced colony formation and metastasis formation of MDA-MB-231 human breast cancer cells

✍ Scribed by Adwan, Hassan; Bäuerle, Tobias J; Berger, Martin R

Book ID
110019065
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
211 KB
Volume
11
Category
Article
ISSN
0929-1903

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## Abstract Metastasis into the skeleton is a serious complication of certain neoplastic diseases such as breast, prostate and lung cancer, but the reasons for this osteotropism are poorly understood. Our aim was to establish a physiologically relevant animal model that is characterized by osteolyt