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Downregulation of miR-138 is associated with overexpression of human telomerase reverse transcriptase protein in human anaplastic thyroid carcinoma cell lines

✍ Scribed by Shingo Mitomo; Chihaya Maesawa; Satoshi Ogasawara; Takeshi Iwaya; Masahiko Shibazaki; Akiko Yashima-Abo; Koji Kotani; Hiroki Oikawa; Eiich Sakurai; Naoko Izutsu; Kuniyuki Kato; Hideaki Komatsu; Kenichro Ikeda; Go Wakabayashi; Tomoyuki Masuda


Book ID
108584061
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
271 KB
Volume
99
Category
Article
ISSN
1347-9032

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## Abstract It has been previously demonstrated that human carcinomas express interleukin‐2 receptor (IL‐2R) α, β, and γ chains. The β and γ chains of IL‐2R have intermediate binding affinity for IL‐2 and are responsible for the intracellular signaling cascades after IL‐2 stimulation. IL‐2Rα lacks