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Downregulation of microRNAs-143 and -145 in B-cell malignancies

โœ Scribed by Yukihiro Akao; Yoshihito Nakagawa; Yukio Kitade; Tomohiro Kinoshita; Tomoki Naoe

Book ID
108584015
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
496 KB
Volume
98
Category
Article
ISSN
1347-9032

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## Background: Mir-143 and mir-145 are believed to function as colon cancer tumor suppressors, as they inhibit colon cancer cell growth and are downregulated in sporadic colonic tumors. we speculated that mir-143 and mir-145 might also be downregulated and contribute to malignant transformation of