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Downregulation of DBC1 expression in acute lymphoblastic leukaemia is mediated by aberrant methylation of its promoter

✍ Scribed by Edurne San José-Enériz; Xabier Agirre; José Román-Gómez; Lucia Cordeu; Leire Garate; Antonio Jiménez-Velasco; Iria Vázquez; María José Calasanz; Anabel Heiniger; Antonio Torres; Felipe Prósper


Book ID
108673801
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
259 KB
Volume
134
Category
Article
ISSN
0007-1048

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## Abstract EGF‐containing fibulin‐like extracellular matrix protein 1 (EFEMP1) was recently described as an antagonist of angiogenesis. Motivated by a strong dependence of tumor growth and metastasis on angiogenesis, we investigated the role of EFEMP1 in human breast cancer. We applied RNA microar