## Abstract Many colorectal tumors lose or downregulate cell surface expression of MHC class I molecules conferring resistance to T‐cell‐mediated attack. It has been suggested that this phenomenon is due to __in vivo__ immune‐tumor interactions. However, evidence of the impact of MHC class I loss o
✦ LIBER ✦
Downregulation of caspase-9 is a frequent event in patients with stage II colorectal cancer and correlates with poor clinical outcome
✍ Scribed by X.-G. Shen; C. Wang; Y. Li; L. Wang; B. Zhou; B. Xu; X. Jiang; Z.-G. Zhou; X.-F. Sun
- Book ID
- 109043517
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 118 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1462-8910
No coin nor oath required. For personal study only.
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## Abstract Cell adhesion molecule 1 (CADM1/TSLC1), a putative tumor suppressor involving in cell adhesion, proliferation and apoptosis, is frequently inactivated in several carcinomas due to promoter hypermethylation. But alterations of CADM1/TSLC1 in colorectal carcinogenesis and clinical signifi