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Downregulation of AMP-activated protein kinase by Cidea-mediated ubiquitination and degradation in brown adipose tissue

✍ Scribed by Qi, Jingzong; Gong, Jingyi; Zhao, Tongjin; Zhao, Jie; Lam, Penny; Ye, Jing; Li, John Zhong; Wu, Jiawei; Zhou, Hai-Meng; Li, Peng


Book ID
109849720
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
415 KB
Volume
27
Category
Article
ISSN
0261-4189

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## Abstract Brief periods of ischemia and reperfusion that precede sustained ischemia lead to a reduction in myocardial infarct size. This phenomenon, known as ischemic preconditioning, is mediated by signaling pathway(s) that is complex and yet to be fully defined. AMP‐activated kinase (AMPK) is a