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Down syndrome and natural family planning

✍ Scribed by James, William H.


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
131 KB
Volume
66
Category
Article
ISSN
0148-7299

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✦ Synopsis


Castilla et al. [1995] report that users of natural family planning (NFP) produced no excess of Down syndrome (DS) infants. The finding is relevant to the question of whether DS is sometimes the consequence of the fertilization of an oocyte which is "overripe." That question achieved prominence in the hypothesis of German [ 19681 that the decline in coital rate with maternal age results in a rise in the proportion of such late fertilizations, thus accounting for the maternal age effect in DS. It was shown mathematically that this decline


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