Down-regulation of the phosphoenolpyruvate carboxykinase gene in human colon tumors and induction by omega-3 fatty acids
β Scribed by Jean-Marc Blouin; Sylvie Bortoli; Magali Nacfer; Martine Collinet; Graziella Penot; Pierre Laurent-Puig; Claude Forest
- Book ID
- 116309284
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 376 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0300-9084
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Phosphoenolpyruvate carboxykinase (PEPCK) exerts a glyceroneogenic function in adipocytes in which transcription of its gene is increased by unsaturated fatty acids and fibrates. We used cultured rat adipose tissue fragments and 3T3-F442A adipocytes to show that the antidiabetic thiazolidinedione BR
## Abstract Polyunsaturated fatty acids (PUFAs) and 3βthia fatty acids are hypolipidemic and decrease insulin resistance in Type II diabetic animals. To exert such an action, these FAs could decrease adipose tissue lipolysis or increase esterification. Glyceroneogenesis is an important metabolic pa
The influence of recombinant human interleukin-6, the major mediator of the inflammatory response in liver, on the glucagon-and insulin-dependent induction of the phosphoenolpyruvate carboqkinase and glucokinase gene, respectively, was monitored on the level of gene transcription, mRNA abundance and