Mechanism of down-regulation of L-type C
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Eikichi Ihara; Katsuya Hirano; Mayumi Hirano; Junji Nishimura; Hajime Nawata; Hi
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Article
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2002
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John Wiley and Sons
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English
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The mechanism of down-regulation of L-type Ca(2+) channel (L-VOC) was investigated in rat aortic smooth muscle cells in primary culture. On culture days 3-5, the cells actively incorporated the 5-bromo-2'-deoxy-uridine (BrdU), and did not respond to K(+) depolarization nor express alpha(1C) subunit