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Down-regulation of the Inositol 1,4,5-Trisphosphate Receptor in Mouse Eggs Following Fertilization or Parthenogenetic Activation

✍ Scribed by Teru Jellerette; Chang Li He; Hua Wu; Jan B. Parys; Rafael A. Fissore


Book ID
115598423
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
464 KB
Volume
223
Category
Article
ISSN
0012-1606

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Activation of inositol 1,4,5-trisphospha
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Injection of inositol 1,4,5-trisphosphate (InsP 3 ) into fertilized Xenopus eggs induced transient changes in cell shape. The region around the injected site contracted during the first 2 min, followed by swelling. These changes which initiated at the injected site extended toward the opposite side.