𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Down-regulation of stathmin is required for TGF-β inducible early gene 1 induced growth inhibition of pancreatic cancer cells

✍ Scribed by Lei Jiang; Yangchao Chen; Chu-yan Chan; Xin Wang; Lin Lin; Ming-liang He; Marie C.M. Lin; David T. Yew; Joseph J.Y. Sung; Ji-Cheng Li; Hsiang-fu Kung

Book ID
116334988
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
266 KB
Volume
274
Category
Article
ISSN
0304-3835

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Transcriptional regulation of Smad2 is r
Transcriptional regulation of Smad2 is required for enhancement of TGFβ/Smad signaling by TGFβ inducible early gene
✍ Steven A. Johnsen; Malayannan Subramaniam; Takenobu Katagiri; Ralf Janknecht; Th 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 178 KB

TGFbeta inducible early gene (TIEG) is a novel Krüppel-like transcriptional repressor that was recently shown to increase the activity of the TGFbeta/Smad signal transduction pathway by relieving negative feedback through repression of the inhibitory Smad7. Interestingly, while Smad7 is required for

Antiangiogenic activity of genistein in
Antiangiogenic activity of genistein in pancreatic carcinoma cells is mediated by the inhibition of hypoxia-inducible factor-1 and the down-regulation of VEGF gene expression
✍ Peter Büchler; Howard A. Reber; Markus W. Büchler; Helmut Friess; Robert S. Lave 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 281 KB 👁 2 views

## Abstract ## BACKGROUND Previous reports indicate that Genistein, a naturally occurring isoflavonoid, exhibits strong antiangiogenic activity. The underlying mechanism of inhibition, however, remains unclear. Among the biologic effects of Genistein are the inhibition of tyrosine kinases and the