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Down-regulation of specific gene expression by double-strand RNA induces neural stem cell differentiationin vitro

โœ Scribed by Tieqiao Wen; Hailong Li; Hongsheng Song; Fuxue Chen; Cuiping Zhao; Wei Lu; Kuiyi Bao; Ye Jin

Book ID
106457463
Publisher
Springer
Year
2005
Tongue
English
Weight
267 KB
Volume
275
Category
Article
ISSN
0300-8177

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Prolonged down regulation of specific ge
Prolonged down regulation of specific gene expression in nucleus pulposus cell mediated by RNA interference in vitro
โœ Kenichiro Kakutani; Kotaro Nishida; Koki Uno; Toru Takada; Takatoshi Shimomura; ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 302 KB

## Abstract To investigate the efficacies and the longevity of RNA interference in nucleus pulposus cells from rat and human, two reporter luciferase plasmids (__Firefly__ and __Renilla__) were used. These plasmids were cotransfected with siRNA targeting __Firefly__ luciferase to the nucleus pulpos