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Down-regulation of mitofusin-2 expression in cardiac hypertrophy in vitro and in vivo

✍ Scribed by Lu Fang; Xiao-Lei Moore; Xiao-Ming Gao; Anthony M. Dart; Yean Leng Lim; Xiao-Jun Du


Book ID
116719096
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
366 KB
Volume
80
Category
Article
ISSN
0024-3205

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## Abstract Both __Tbx1__ and retinoic acid (RA) are key players in embryonic pharyngeal development; loss of __Tbx1__ produces DiGeorge syndrome‐like phenotypes in mouse models as does disruption of retinoic acid homeostasis. We have demonstrated that perturbation of retinoic acid levels in the av