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Down-regulation of L-type calcium channels in inflamed circular smooth muscle cells of the canine colon

โœ Scribed by Xiaorong Liu; Nancy J. Rusch; Joerg Striessnig; Sushil K. Sarna


Book ID
119756097
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
245 KB
Volume
120
Category
Article
ISSN
0016-5085

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โœ Eikichi Ihara; Katsuya Hirano; Mayumi Hirano; Junji Nishimura; Hajime Nawata; Hi ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 223 KB

The mechanism of down-regulation of L-type Ca(2+) channel (L-VOC) was investigated in rat aortic smooth muscle cells in primary culture. On culture days 3-5, the cells actively incorporated the 5-bromo-2'-deoxy-uridine (BrdU), and did not respond to K(+) depolarization nor express alpha(1C) subunit