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Down-regulation of endothelial cell estrogen receptor expression by the inflammation promoter LPS

✍ Scribed by Anders Holm; Kristina E. Andersson; Ina Nordström; Per Hellstrand; Bengt-Olof Nilsson

Book ID: 116734718
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 631 KB
Volume: 319
Category: Article
ISSN: 0303-7207
DOI: 10.1016/j.mce.2010.01.002

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## Abstract In previous studies on HeLa cells we demonstrated estrogen‐responsiveness of the epidermal growth factor receptor (EGFR) gene, as 17β‐estradiol (E~2~) and selective estrogen receptor modulators (SERMs) genistein (G), daidzein (D), and 4‐hydroxytamoxifen (4OH‐T) modulated its transcripti