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Down-regulation of DNA methyltransferase 3B in staurosporine-induced apoptosis and its mechanism in human hepatocarcinoma cell lines

✍ Scribed by Chao Zhao, Peng Yin, Chuanzhong Mei, Na Li…


Book ID
120748544
Publisher
Springer
Year
2013
Tongue
English
Weight
537 KB
Volume
376
Category
Article
ISSN
0300-8177

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## Abstract DNA methyltransferases (DNMTs) are essential for maintenance of aberrant methylation in cancer cells and play important roles in the development of cancers. Unregulated activation of PI3K/Akt pathway is a prominent feature of many human cancers including human hepatocellular carcinoma (