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Down regulation of CYP 1A1 by glucocorticoids in trout hepatocytes in vitro

✍ Scribed by A. K. Dasmahapatra; P. C. Lee

Book ID
112803754
Publisher
Society for In Vitro Biology
Year
1993
Tongue
English
Weight
924 KB
Volume
29
Category
Article
ISSN
1475-2689

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## Abstract Cytochrome P450 1A2 (CYP1A2) is constitutively expressed in the mouse liver, but the constitutive expression progressively declines to an undetectable level in isolated hepatocytes. In this study, CYP1A2 was induced in hepatocytes exposed to the histone deacetylase inhibitors trichostat