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Down-regulation of cFLIP following reovirus infection sensitizes human ovarian cancer cells to TRAIL-induced apoptosis

✍ Scribed by Penny Clarke; Kenneth L Tyler


Publisher
Springer
Year
2006
Tongue
English
Weight
554 KB
Volume
12
Category
Article
ISSN
1360-8185

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## Abstract This study demonstrates that combined treatment with subtoxic doses of quercetin (3′,3′,4′,5,7‐pentahydroxyflavone), a flavonoid found in many fruits and vegetables, plus tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) induces rapid apoptosis in TRAIL‐resistant hepatocel