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Down-regulation of cellular proto-oncogenes during inhibition of rat parotid acinar cell proliferation

✍ Scribed by Seok-Woo Lee; Karnam R. Purushotham; Trevor Littlewood; Gerard Evan; Tivadar Zelles; Jofsef Blazsek; Yoichi Nakagawa; Michael G. Humphreys-Beher


Book ID
119121564
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
513 KB
Volume
1135
Category
Article
ISSN
0167-4889

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## Abstract MCF‐ 10A is a spontaneously immortalized, non‐transformed human mammary epithelial cell line. We have recently obtained MCF‐ 10A clones (MCF‐ 1OA HE cells) that are transformed following over‐expression of both a human point‐mutated c‐Ha‐__ras__ and the c‐__erb__B‐2 proto‐oncogenes. Two