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Down-regulation of CD59 sensitizes prostate carcinoma cells to complement attack and inhibits proliferation

✍ Scribed by Wenhan Li; Stefan Schultz; Nicolas Geiss; Michael Kirschfink

Book ID: 116756538
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 58 KB
Volume: 44
Category: Article
ISSN: 0161-5890
DOI: 10.1016/j.molimm.2007.06.092

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## Abstract We have recently shown that an adenovirus carrying REIC/Dkk‐3 (Ad‐REIC) exhibits a potent tumor‐specific cell‐killing function for various human cancers. It has also become evident that some human cancers are resistant to Ad‐REIC‐induced apoptosis. The aim of the present study was to de