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Down-regulation of cardiac bradykinin B2 receptors and eNOs mRNA in rats with remnant kidneys

✍ Scribed by Wan Huaibin; Tu Ling; Liu Xiaoqing; Deng Juanjuan


Publisher
Springer-Verlag
Year
2005
Tongue
Chinese
Weight
290 KB
Volume
25
Category
Article
ISSN
0510-9752

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## Abstract Rat1 fibroblasts stably transfected with the rat angiotensin II (AngII) AT1a and bradykinin (BK) B2 receptor cDNAs gained the ability to bind Ang II and BK. Wild‐type Rat1 cells bound neither ligand. Exposure to either effector led to characteristic GΞ±i and GΞ±q signal cascades, the rele