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Down-regulation of apoptosis-related Bcl-2 but not Bax protein in apocrine metaplasia of the breast: relationship to oestrogen and progesterone receptors

โœ Scribed by A.A. Selim; S. Jordan; C.A. Wells


Book ID
114317133
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
145 KB
Volume
6
Category
Article
ISSN
0960-9776

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Down-regulation of apoptosis-related bcl
โœ Besim Ogretmen; Ahmad R. Safa ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 797 KB

Recent studies have shown that high levels of the apoptosisrelated proteins bcl-2 and bcl-x, increase, while over-expression of bcl-x, or bax decreases, resistance to drugs that induce apoptosis in some human cancer cells. In the present report, we investigated whether expression of these apoptosis-