Down-regulation in the insulin-like growth factor (IGF) axis during hibernation in the golden-mantled ground squirrel,Spermophilus lateralis: IGF-I and the IGF-binding proteins (IGFBPs)

Effect of insulin-like growth factor (IG

Effect of insulin-like growth factor (IGF)-I and Des (1-3) IGF-I on the level of IGF binding protein-3 and IGF binding protein-3 mRNA in cultured porcine embryonic muscle cells

✍ F. Yang; B.J. Johnson; M.E. White; M.R. Hathaway; W.R. Dayton 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 219 KB 👁 1 views

Insulin-like growth factor binding protein (IGFBP)-3 effects proliferation and differentiation of numerous cell types by binding to insulin-like growth factors (IGF) and attenuating their activity or by directly affecting cells in an IGFindependent manner. Consequently, IGFBPs produced by specific c