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Down-regulation and promoter methylation of tissue inhibitor of metalloproteinase 3 in choriocarcinoma

โœ Scribed by Huichen Feng; Annie N.Y Cheung; Wei-Cheng Xue; Yanling Wang; Xianghong Wang; Songbin Fu; Qi Wang; Hextan Y.S Ngan; Sai-Wah Tsao

Book ID
113959320
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
310 KB
Volume
94
Category
Article
ISSN
0090-8258

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## Abstract Extracellular matrix (ECM) remodeling is involved in many cellular properties such as division, migration, differentiation, and death. The turnover of ECM is regulated by matrix metalloproteinases (MMPs) and the MMPs are inhibited by the tissue inhibitors of metalloproteinases (TIMPs).