Down-regulated expression of cytochrome P450 related genes involved in hepatocellular carcinoma
โ Scribed by Xiufeng Liu; Ruihua Shi; Xuehao Wang; Guoxin Zhang; Hong Zhu; Hengjun Gao; Shukui Qin
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 263 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1610-1979
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## Background: The suppression of apoptosis is an important factor in tumor progression in hepatocellular carcinoma (hcc). however, to the authors knowledge the clinicopathologic importance of the expression of apoptosis-related genes (bcl-2, bax, and survivin) in hcc remains unclear. in the curren
## Abstract Cytochrome P450โ2E1 (CYP2E1) is one of the major hepatic enzymes involved in the metabolism of procarcinogen. Our study aimed to investigate the differential expression level of __CYP2E1__ and its clinicopathological significance in hepatocellular carcinoma (HCC). __CYP2E1__ revealed lo
teers administered interferon, decreases in the metabolism Administration of interferons of both the gamma and of antipyrine, 16 theophylline, [18] erythromycin, 20 and hexoalfa/beta classes down-regulates hepatic cytochrome barbital 18 have been observed. Cytokines, including inter-P450 (CYP) genes