Double trisomy in spontaneous abortions
โ Scribed by K. S. Reddy
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 68 KB
- Volume
- 101
- Category
- Article
- ISSN
- 0340-6717
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In a recent report of chromosome analysis of a 17-week fetus, triple trisomy was found, i.e. 4 9 , X X X , + 5 , + 1 3 (Pettenati and Rao 1991). The authors comment on the rarity of this event since they found only one other reference to such a finding in an abortus with 49,XX,+2, + 5 , + 8 (Kajii e
The relationship of paternal age to specific types of trisomy and to chromosomally normal loss was investigated in data drawn from a case-control study of spontaneous abortions. Differences in paternal age between karyotype groups and controls delivering after 28 weeks gestation were tested using an
Chromosome heteromorphisms of 34 trisomic abortuses and their parents were compared to determine the origin of the extra chromosome. Fourteen of the trisomies were maternal in origin, ten resulting from a first-meiotic-division error and four from either first- or second-meiotic-division errors. No