Double-stranded RNA-dependent protein kinase is required for bone calcification in MC3T3-E1 cells in vitro
β Scribed by Kaya Yoshida; Hirohiko Okamura; Bruna Rabelo Amorim; Akiko Ozaki; Hiroaki Tanaka; Hiroyuki Morimoto; Tatsuji Haneji
- Book ID
- 118506273
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 293 KB
- Volume
- 311
- Category
- Article
- ISSN
- 0014-4827
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Time-dependent changes of the [3H]-proline-labeled noncollagenous proteins synthesized by the osteogenic cell-line MC3T3-E1 were analyzed over a range starting from cell confluency to 13 days after confluency during which time cells formed a bone-like structure. It was found that the 40 kDa protein