DOUBLE-STRANDED RNA AND BACTERIAL LPS-INDUCED ACTIVATION OF VASCULAR SMOOTH MUSCLE CELLS: ROLE OF TOLL-LIKE RECEPTOR 3 AND TOLL-LIKE RECEPTOR 4
β Scribed by Xin Yang; Kelly Schultz; Daniel Coriolan; Katherine A Fitzgerald; Douglas T Golenbock; Debbie Beasley
- Book ID
- 116342157
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 38 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1054-8807
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## Abstract Endotoxemia by bacterial lipopolysaccharide (LPS) has been reported to affect gut motility specifically depending on Tollβlike receptor 4 activation (TLR4). However, the direct impact of LPS ligation to TLR4 on human smooth muscle cells (HSMC) activity still remains to be elucidated. Th
## Abstract The cell types of the gut expressing Tollβlike receptor 4, which recognizes specifically bacterial lipopolysaccharides, as well as the functionality of this receptor, have remained controversial. We aimed to clarify these issues. Mouse and human intestinal specimens were stained immunoh