Double minute chromosomes. A bone marrow indicator of neuroblastoma metastasis and relapse: Two case reports

Double minute chromosomes in monoblastic

Double minute chromosomes in monoblastic (M5) and myeloblastic (M2) acute myeloid leukemia: Two case reports and a review of literature

✍ Leno Thomas; Judith Stamberg; Ivana Gojo; Yi Ning; Aaron P. Rapoport 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 153 KB 👁 2 views

## Abstract Double minutes (dmin) are small, paired chromatin bodies that lack a centromere and represent a form of extrachromosomal gene amplification. Although they have been found in a variety of solid tumors, their presence in hematological malignancies, especially acute myeloid leukemia (AML),