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Double heterozygosity of the β-malay and a novel β-thalassemia gene in a thai patient

✍ Scribed by Supan Fucharoen; Goonnapa Fucharoen; Vichai Laosombat; Yasuyuki Fukumaki

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
240 KB
Volume
38
Category
Article
ISSN
0361-8609

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✦ Synopsis

The (3-globin genes from a Thai patient compound heterozygous for p'and Pothalassemias were investigated. Amplification and DNA analysis of genomic DNA by the polymerase chain reaction procedure permitted the identification of the p-Malay mutation (p 19;AAC-AGC) in one allele and a novel pO-thalassemia mutation (41 ;TTC-TT) in another allele.

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