✦ LIBER ✦

Dosimetry of18F-Labeled Tyrosine Kinase Inhibitor SKI-249380, a Dasatinib-Tracer for PET Imaging

✍ Scribed by Mark P. S. Dunphy; Pat Zanzonico; Darren Veach; Romel Somwar; Nagavarakishore Pillarsetty; Jason Lewis; Steven Larson

Publisher: Springer-Verlag
Year: 2010
Tongue: English
Weight: 358 KB
Volume: 14
Category: Article
ISSN: 1536-1632
DOI: 10.1007/s11307-010-0462-2

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A fully automated two-step synthesis of

A fully automated two-step synthesis of an 18F-labelled tyrosine kinase inhibitor for EGFR kinase activity imaging in tumors

✍ D. Kobus; Y. Giesen; R. Ullrich; H. Backes; B. Neumaier 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 439 KB

PET with18F-labelled choline-based trace

PET with18F-labelled choline-based tracers for tumour imaging: a review of the literature

✍ Koen Mertens; Dominique Slaets; Bieke Lambert; Marjan Acou; Filip De Vos; Ingebo 📂 Article 📅 2010 🏛 Springer 🌐 English ⚖ 140 KB

Fluorine-18 labeling of 6,7-disubstitute

Fluorine-18 labeling of 6,7-disubstituted anilinoquinazoline derivatives for positron emission tomography (PET) imaging of tyrosine kinase receptors: synthesis of 18F-Iressa and related molecular probes

✍ Yann Seimbille; Michael E. Phelps; Johannes Czernin; Daniel H. S. Silverman 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 157 KB

Inhibitors of tyrosine kinase enzymatic activity represent a promising new class of antineoplastic agents. Although clinical studies performed over the last decade give more insight on the potential therapeutic applications of such drugs, identification of the individual patients who might benefit f

A first synthesis of 18F-radiolabeled la

A first synthesis of 18F-radiolabeled lapatinib: a potential tracer for positron emission tomographic imaging of ErbB1/ErbB2 tyrosine kinase activity

✍ Falguni Basuli; Haitao Wu; Changhui Li; Zhen-Dan Shi; Agnieszka Sulima; Gary L. 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 596 KB

Fluorine‐18‐labeled lapatinib has been successfully synthesized for the first time by the reaction of a dimethylformamide solution of __meta__‐[^18^F]fluorobenzylbromide with a Boc‐protected lapatinib precursor fragment. The reaction proceeded in the presence of K~2~CO~3~ at 110 °C for 10 min in a m