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Dosimetry of N 6 -Formyllysine Adducts Following [ 13 C 2 H 2 ]-Formaldehyde Exposures in Rats

✍ Scribed by Edrissi, Bahar; Taghizadeh, Koli; Moeller, Benjamin C.; Kracko, Dean; Doyle-Eisele, Melanie; Swenberg, James A.; Dedon, Peter C.


Book ID
125950985
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
617 KB
Volume
26
Category
Article
ISSN
0893-228X

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## Abstract Localized, water‐suppressed ^1^H‐[^13^C]‐NMR spectroscopy was used to detect ^13^C‐label accumulation in cerebral metabolites following the intravenous infusion of [1,6‐^13^C~2~]‐glucose (Glc). The ^1^H‐[^13^C]‐NMR method, based on adiabatic RF pulses, 3D image‐selected in vivo spectros