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Dose-response relationship toxicity of CAR activators in mice

โœ Scribed by Clifford Elcombe


Book ID
116925066
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
42 KB
Volume
211
Category
Article
ISSN
0378-4274

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6-Mercaptopurine riboside (6-MF'r) is used as a cytostatic chemotherapeutic. The teratogenic potential in rodents has been well known for several decades. In this study, the teratogenic risk of low doses of 6-MPr in NMRI mice was estimated based on a dose-response study. The effective doses correspo