Mutations of the p53 tumor suppressor gene are frequent in lung cancers. It is suggested that p53 mutations are associated with smoking-induced lung carcinogenesis. We examined p53 mutations in 53 lung cancers by analyzing reverse transcription-polymerase chain reaction-single strand conformation po
โฆ LIBER โฆ
Dose-response relationship in tobacco-related cancers of bladder and lung: A biochemical interpretation
โ Scribed by Paolo Vineis; Michael Alavanja; Seymour Garte
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- French
- Weight
- 76 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0020-7136
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โฆ Synopsis
The purpose of our study is to address the challenge of evaluating carcinogenic effects at low levels of exposure to carcinogens. We examine the shape of the dose-response relationship between tobacco smoking and cancers of the bladder and lung, and the implications for the evaluation of the effects of exposure at lower levels, for example, environmental tobacco smoke (ETS).
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