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Dose Response for Amphetamine-Induced Changes in Dopamine Levels in Push-Pull Perfusates of Rat Striatum

โœ Scribed by Ronald Kuczenski


Book ID
111173808
Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
700 KB
Volume
46
Category
Article
ISSN
0022-3042

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After 5 days of continuous treatment with d-amphetamine base in doses greater than 0.5 mg/kg/h maintained by subcutaneously implanted osmotic minipumps, specific binding of 3H-spiroperidol was reduced in rat striatum and frontal cortex as previously reported. These effects were dose-dependent at low