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Dose-response correlation for the induction of respiratory-tract tumours in Syrian golden hamsters by intratracheal instillations of benzo(a)pyrene

✍ Scribed by V.J. Feron; D. De Jong; P. Emmelot


Book ID
113145363
Publisher
Elsevier Science
Year
1973
Weight
242 KB
Volume
9
Category
Article
ISSN
0014-2964

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## Abstract To study the role of particle size of benzo (a) pyrene (BP) in the induction of respiratory tract tumours, goups of hamsters were given 52 weekly intratracheal instillations of fine (77% < 5.2 ΞΌm; 3% < 1.3 ΞΌan) or coarse (77 y 42 ΞΌm; 0% < 10 ΞΌm) BP particles suspended in gelatin‐0.9% Na