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Dose-related inhibition of brain and plasma cholinesterase in neonatal and adult rats following sublethal organophosphate exposures

✍ Scribed by Carey N. Pope; Tamal K. Chakraborti


Book ID
118406830
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
472 KB
Volume
73
Category
Article
ISSN
0300-483X

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The purpose of this study was to evaluate the relative sensitivity of neonatal and adult CD rats to manganese-induced neurotoxicity. Identical oral manganese chloride (MnCl(2)) doses (0, 25, or 50 mg kg(-1) body wt. day(-1)) were given to neonatal rats throughout lactation (i.e. from postnatal day (