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Dose-related hepatotoxicity of 1,1,2-trichloro-1,2,2-trifluoroethane in short-term intermittent inhalation exposure in rats

✍ Scribed by H. Vainio; J. Nickels; T. Heinonen


Book ID
103656863
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
848 KB
Volume
18
Category
Article
ISSN
0300-483X

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The hepatic effects of 1,2-dichloropropane (DCP) were investigated in male Wistar rats exposed to 15, 50, 100, 250, 450, 1000, 1300, 1800 or 4900 mg DCP At the end of a 4-h period of exposure, average blood DCP levels were 0.025 and 5.38 pg ml-' in animals treated with 15 and 1300 mg m-3, respective