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Dose-intensive approaches to ovarian cancer

โœ Scribed by Nicholas Lambrou; Edward L. Trimble


Publisher
Current Science Inc.
Year
1999
Tongue
English
Weight
230 KB
Volume
1
Category
Article
ISSN
1523-3790

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More than 90% of epithelial ovarian cancers arise from single cells. Malignant transformation can be associated with a number of molecular alterations including upregulation of tyrosine kinases and phosphatases, physiologic activation of ras, mutation of p53, amplification of myc, and increased acti