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Dose-finding study and pharmacogenomic analysis of fixed-rate infusion of gemcitabine, irinotecan and bevacizumab in pretreated metastatic colorectal cancer patients

✍ Scribed by Abajo, A; Rodriguez, J; Bitarte, N; Zarate, R; Boni, V; Ponz, M; Chopitea, A; Bandres, E; Garcia-Foncillas, J


Book ID
110000691
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
333 KB
Volume
103
Category
Article
ISSN
0007-0920

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## Abstract ## BACKGROUND. The combination of a fixed dose rate (FDR) infusion of gemcitabine and irinotecan may have a synergistic effect in the treatment of patients with advanced and metastatic pancreatic and biliary cancer. The current study was conducted to determine the dose‐limiting toxicit