This reference provides a concise overview of the key principles in dose selection and optimization and demonstrates applicability to recent successful new drug applications. Compiling key issues and current research on safety, efficacy, and clinical pharmacology, and PK-PD, this volume critically h
Dose finding in drug development
β Scribed by Naitee Ting
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Leaves
- 261
- Series
- Statistics for biology and health
- Category
- Library
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Arguably the most difficult aspect of drug development, once proof-of-concept is achieved for a novel mechanism, is defining the βrightβ dose. Indeed, the question rapidly expands to right for whom? An individual? A population? A specific disease? A unique demographic? The answers can yield a dizzyi
A consolidated and comprehensive reference on ligand-binding assaysLigand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry. Yet, outside of the Crystal
<b>A consolidated and comprehensive reference on ligand-binding assays <p> Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry. Yet, outside