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Dose escalation, treatment protraction, and the steepness of the dose-response curve for squamous cell carcinoma of the head and neck

✍ Scribed by Bentzen, Søren M.

Book ID
121779129
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
267 KB
Volume
34
Category
Article
ISSN
0167-8140

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## Abstract Eleven patients with squamous carcinoma of the head and neck who were scheduled for surgical resection or endoscopic biopsy of tumor received 15 mg/m^2^ of methotrexate (MTX). Samples of tumor, normal mucosa, and plasma were obtained at surgery or endoscopy, 18‐24 hours after the last M