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Dose effects of secobarbital in a Sternberg memory scanning task

✍ Scribed by Harold L. Williams; Orvis H. Rundell; Ladngrave T. Smith

Publisher: Springer
Year: 1981
Tongue: English
Weight: 460 KB
Volume: 72
Category: Article
ISSN: 0033-3158
DOI: 10.1007/bf00431650

No coin nor oath required. For personal study only.

✦ Synopsis

Mean reaction times obtained in a Sternberg memory-scanning task were examined for the effects of secobarbital at two doses (1.47 mg/kg and 2.94 mg/kg) spanning the dose range commonly used in clinical practice. Both doses slowed reaction time significantly, with a more pronounced effect at the higher dose. The discriminability of the probe stimulus interacted with the barbiturate, producing a hyperadditive effect on reaction time, but only at the high dose. There were no other significant interaction effects involving the drug. These data are interpreted as additional support for an hypothesis localizing the effects of secobarbital to stimulus-encoding stages in the reaction process.

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