Endotoxemia decreases the dose requirement for anesthetics but no data are available for propofol. A rat model was used in which the influence of endotoxin administration on the pharmacokinetics and pharmacodynamics of propofol was investigated. Chronically instrumented rats were randomly allocated
Dose effects of propofol on hemodynamic and cytokine responses to endotoxemia in rats
โ Scribed by Yasuhiro Takemoto
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 148 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0913-8668
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