Dose dependent uptake of125I-toluidine blue and of75Se-selenomethionine in the parathyroids of rabbits
✍ Scribed by Eldar Normann; Trygve Eide; Per Lund; Trine Normann
- Book ID
- 104713018
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 244 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0340-6997
No coin nor oath required. For personal study only.
✦ Synopsis
Different dosages of 125I-toluidine blue and 75Se-selenomethionine were injected intravenously into rabbits, and the concentration of radioactivity was measured in the parathyroids and surrounding tissues. The response of i.v. injected glucagon was also determined. It was found that 0.16 mg 125I-toluidine blue gave a concentration ratio of parathyroid/thyroid and parathyroid/muscle which was significantly higher than both lower and higher doses at 1 minute after i.v. injection of the labelled dye. Glucagon had little or no effect on the uptake of 125I-toluidine blue and 75Se-selenomethionine.