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Dose dependent inhibition of B-16 melanoma growth in vivo by a synthetic analogue of PGE2

โœ Scribed by M. Gabriella Santoro; Gordon W. Philpott; Bernard M. Jaffe


Book ID
119048437
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
327 KB
Volume
14
Category
Article
ISSN
0090-6980

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The synthetic matrix metalloproteinase inhibitor batimastat was tested for its ability to inhibit growth and metastatic spread of the B16-BL6 murine melanoma in syngeneic C57BL/6N mice. lntraperitoneal administration of batimastat resulted in a significant inhibition in the number of lung colonies p