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Dose-dependent inhibition by cyclosporine a of the induction of pancreatic ornithine decarboxylase (ODC) in rats

✍ Scribed by Christian Löser; Fritz Stöckmann; Ulrich R. Fälsch; Werner Creutzfeldt

Book ID
112938904
Publisher
Springer US
Year
1989
Tongue
English
Weight
839 KB
Volume
5
Category
Article
ISSN
1941-6628

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## Abstract Overexpression of ornithine decarboxylase (ODC) is an important oncogenic event in tumorigenesis. Although __ODC__ was one of the first genes described whose product is inducible by 12‐__O__‐tetradecanoylphorbol‐13‐acetate (TPA), the mechanisms of __ODC__ transcriptional regulation have