✦ LIBER ✦

Dose-dependent elimination of propranolol and its major metabolites in humans

✍ Scribed by Bernie M. Silber; Nicholas H. G. Holford; Sidney Riegelman

Publisher: John Wiley and Sons
Year: 1983
Tongue: English
Weight: 747 KB
Volume: 72
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600720703

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Urinary excretion of probenecid and its

Urinary excretion of probenecid and its metabolites in humans as a function of dose

✍ Srikumaran Melethil; Walter D. Conway 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 English ⚖ 493 KB 👁 1 views

Biliary elimination of low-dose methotre

Biliary elimination of low-dose methotrexate in humans

✍ Bernd Nuernberg; Rachelle Koehnke; Marilyn Solsky; John Hoffman; Daniel E. Furst 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 438 KB 👁 2 views

Single dose kinetics of thioridazine and

Single dose kinetics of thioridazine and its two psychoactive metabolites in healthy humans: A dose proportionality study

✍ B. S. Chakraborty; K. K. Midha; G. McKay; E. M. Hawes; J. W. Hubbard; E. D. Korc 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 845 KB

Serum protein binding of tolterodine and

Serum protein binding of tolterodine and its major metabolites in humans and several animal species

✍ Ingrid Påhlman; Peter Gozzi 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 151 KB 👁 2 views

The aim of this study was to determine in vitro protein binding of tolterodine and its 5-hydroxymethyl (5-HM) and N-dealkylated metabolites in serum from humans and several animal species at concentrations similar to those obtained in clinical and preclinical studies. Binding of tolterodine and the

Dose-dependent disposition of oral propr

Dose-dependent disposition of oral propranolol in normal subjects

✍ Janis J. Mackichan; Dennis R. Pyszczynski; William J. Jusko 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 376 KB

## Abstract The pharmacokinetics and relative systemic availability or oral propranolol were studied in three healthy volunteers following administration of 10, 40, and 80 mg of propranolol hydrochloride. Plasma concentrations of propranolol were determined using a sensitive and specific fluorometr

Multiple-dose propranolol administration

Multiple-dose propranolol administration does not influence the single dose pharmacokinetics of quinapril and its active metabolite (quinaprilat)

✍ A. M. Horvath; D. Pilon; G. Caillé; W. A. Colburn; J. J. Ferry; G. J. Frank; Y. 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 326 KB

## Abstract To evaluate the influence of multiple dose propranolol administration on the single dose pharmacokinetics of quinapril and its active metabolite, quinaprilat, a drug‐drug interaction study was performed in ten healthy volunteers. Each subject received a single 20 mg quinapril oral dose